Brain and blood biomarkers of chronic traumatic encephalopathy
نویسندگان
چکیده
منابع مشابه
Imaging in Chronic Traumatic Encephalopathy and Traumatic Brain Injury
CONTEXT The diagnosis of chronic traumatic encephalopathy (CTE) can only be made pathologically, and there is no concordance of defined clinical criteria for premorbid diagnosis. The absence of established criteria and the insufficient imaging findings to detect this disease in a living athlete are of growing concern. EVIDENCE ACQUISITION The article is a review of the current literature on C...
متن کاملChronic Traumatic Encephalopathy: The Neuropathological Legacy of Traumatic Brain Injury.
Almost a century ago, the first clinical account of the punch-drunk syndrome emerged, describing chronic neurological and neuropsychiatric sequelae occurring in former boxers. Thereafter, throughout the twentieth century, further reports added to our understanding of the neuropathological consequences of a career in boxing, leading to descriptions of a distinct neurodegenerative pathology, term...
متن کاملRepetitive Traumatic Brain Injury and Development of Chronic Traumatic Encephalopathy: A Potential Role for Biomarkers in Diagnosis, Prognosis, and Treatment?
The diagnosis of chronic traumatic encephalopathy (CTE) upon autopsy in a growing number of athletes and soldiers alike has resulted in increased awareness, by both the scientific/medical and lay communities, of the potential for lasting effects of repetitive traumatic brain injury. While the scientific community has come to better understand the clinical presentation and underlying pathophysio...
متن کاملChronic Traumatic Encephalopathy
42 The Hearing Journal May 2017 C oncussions are something of a clinical conundrum. There has been growing concern that one or more blows to the head can cause lasting brain damage, even after symptoms appear to have resolved. The diagnosis of concussions relies on the evaluation of multiple organ symptoms, but it is important to note that patient reports of their symptoms are inherently subjec...
متن کاملLong-term consequences of repetitive brain trauma: chronic traumatic encephalopathy.
Chronic traumatic encephalopathy (CTE) has been linked to participation in contact sports such as boxing and American football. CTE results in a progressive decline of memory and cognition, as well as depression, suicidal behavior, poor impulse control, aggressiveness, parkinsonism, and, eventually, dementia. In some individuals, it is associated with motor neuron disease, referred to as chroni...
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ژورنال
عنوان ژورنال: Nature Reviews Neurology
سال: 2020
ISSN: 1759-4758,1759-4766
DOI: 10.1038/s41582-020-0340-8